Caveolin 2 antibody

Catalog No. ABIN2460105

Product Details anti-Caveolin 2 Antibody

Target: Caveolin 2 (CAV2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caveolin 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CAV2.

Application Details

Application Notes: CAV2 antibody can be used for detection of CAV2 by ELISA at 1:62500. CAV2 antibody can be used for detection of CAV2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CAV2 antibody at -20 °C.

Target Details for Caveolin 2

Target: Caveolin 2 (CAV2)

Alternative Name: CAV2 (CAV2 Products)

Synonyms: CAV antibody, AI447843 antibody, cav-2 antibody, zgc:86696 antibody, wu:fc52e01 antibody, caveolin-2 antibody, CAV-2 antibody, Caveolin-2 antibody, Cav-2 antibody, cav antibody, cav2 antibody, caveolin 2 antibody, caveolin 2 L homeolog antibody, caveolin-2 antibody, Caveolin-2 antibody, CAV2 antibody, Cav2 antibody, cav2.L antibody, cav2 antibody, LOC100093133 antibody, cav-2 antibody

Background: CAV2 is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Two transcript variants encoding distinct isoforms have been identified for this gene. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by one transcript.The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Two transcript variants encoding distinct isoforms have been identified for this gene. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by one transcript.

Molecular Weight: 18 kDa

Gene ID: 858

NCBI Accession: NP_001224

UniProt: P51636

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development