RRN3 antibody

Catalog No. ABIN2460959

Product Details anti-RRN3 Antibody

Target: RRN3 (RRN3 RNA Polymerase I Transcription Factor (RRN3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RRN3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RRN3.

Application Details

Application Notes: RRN3 antibody can be used for detection of RRN3 by ELISA at 1:62500. RRN3 antibody can be used for detection of RRN3 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store RRN3 antibody at -20 °C.

Target Details for RRN3

Target: RRN3 (RRN3 RNA Polymerase I Transcription Factor (RRN3))

Alternative Name: RRN3 (RRN3 Products)

Synonyms: RRN3 antibody, DKFZp459B073 antibody, CG16938 antibody, CG3278 antibody, CG5951 antibody, Dmel\\CG3278 antibody, TIF-1A antibody, TIF-IA antibody, Tif-1A antibody, TifIA antibody, dTIF-IA antibody, dyak_GLEANR_13182 antibody, DyakGE12956 antibody, GE12956 antibody, Tif-IA antibody, A-270G1.2 antibody, TIFIA antibody, RGD1305001 antibody, AL023001 antibody, E130302O19Rik antibody, R75565 antibody, Tif1a antibody, RRN3 homolog, RNA polymerase I transcription factor antibody, RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) antibody, CG3278 gene product from transcript CG3278-RA antibody, GE12956 gene product from transcript GE12956-RA antibody, RRN3 homolog, RNA polymerase I transcription factor L homeolog antibody, RRN3 RNA polymerase I transcription factor homolog (yeast) antibody, RRN3 antibody, rrn3 antibody, Tif-IA antibody, Dyak\Tif-IA antibody, rrn3.L antibody, Rrn3 antibody

Background: In mammals, growth-dependent regulation of RNA polymerase I (Pol I) transcription is mediated by RRN3, an essential initiation factor. It interacts with Pol I in the absence of template DNA, augments Pol I transcription in vivo and rescues transcription in extracts from growth-arrested cells in vitro.

Molecular Weight: 74 kDa

Gene ID: 54700

NCBI Accession: NP_060897

UniProt: Q9NYV6

Pathways: Negative Regulation of intrinsic apoptotic Signaling