KLF6 antibody

Catalog No. ABIN2461181

Product Details anti-KLF6 Antibody

Target: KLF6 (Kruppel-Like Factor 6 (KLF6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLF6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KLF6.

Application Details

Application Notes: KLF6 antibody can be used for detection of KLF6 by ELISA at 1:312500. KLF6 antibody can be used for detection of KLF6 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store KLF6 antibody at -20 °C.

Target Details for KLF6

Target: KLF6 (Kruppel-Like Factor 6 (KLF6))

Alternative Name: KLF6 (KLF6 Products)

Synonyms: gbf antibody, zf9 antibody, bcd1 antibody, cba1 antibody, cpbp antibody, pac1 antibody, st12 antibody, copeb antibody, MGC53475 antibody, KLF6 antibody, MGC127307 antibody, BCD1 antibody, CBA1 antibody, COPEB antibody, CPBP antibody, GBF antibody, PAC1 antibody, ST12 antibody, ZF9 antibody, AI448727 antibody, C86813 antibody, Copeb antibody, FM2 antibody, FM6 antibody, Ierepo1 antibody, Ierepo3 antibody, R75280 antibody, Zf9 antibody, Aa1017 antibody, klf6 antibody, cb538 antibody, wu:fb76d04 antibody, wu:fb92h03 antibody, wu:fe26g06 antibody, wu:fk78f12 antibody, Kruppel-like factor 6 L homeolog antibody, Kruppel like factor 6 antibody, Krueppel-like factor 6 antibody, Kruppel-like factor 6 antibody, Kruppel-like factor 6 S homeolog antibody, Kruppel-like factor 6a antibody, klf6.L antibody, KLF6 antibody, LOC100196412 antibody, klf6 antibody, Klf6 antibody, klf6.S antibody, klf6a antibody

Background: KLF6 is a nuclear protein that has three zinc fingers at the end of its C-terminal domain, a serine/threonine-rich central region, and an acidic domain lying within the N-terminal region. The zinc fingers of this protein are responsible for the specific DNA binding with the guanine-rich core promoter elements. The central region might be involved in activation or posttranslational regulatory pathways, and the acidic N-terminal domain might play an important role in the process of transcriptional activation. It is capable of activating transcription approximately 4-fold either on homologous or heterologous promoters. KLF6 may participate in the regulation and/or maintenance of the basal expression of pregnancy-specific glycoprotein genes and possibly other TATA box-less genes.This gene encodes a nuclear protein that has three zinc fingers at the end of its C-terminal domain, a serine/threonine-rich central region, and an acidic domain lying within the N-terminal region. The zinc fingers of this protein are responsible for the specific DNA binding with the guanine-rich core promoter elements. The central region might be involved in activation or posttranslational regulatory pathways, and the acidic N-terminal domain might play an important role in the process of transcriptional activation. It is capable of activating transcription approximately 4-fold either on homologous or heterologous promoters. The DNA binding and transcriptional activity of this protein, in conjunction with its expression pattern, suggests that this protein may participate in the regulation and/or maintenance of the basal expression of pregnancy-specific glycoprotein genes and possibly other TATA box-less genes. Two transcript variants encoding the same protein have been found for this gene.

Molecular Weight: 32 kDa, 32 kDa

Gene ID: 1316

NCBI Accession: NP_001291

UniProt: Q99612