ANXA6 antibody

Catalog No. ABIN2461374

Product Details anti-ANXA6 Antibody

Target: ANXA6 (Annexin A6 (ANXA6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANXA6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ANXA6.

Application Details

Application Notes: ANXA6 antibody can be used for detection of ANXA6 by ELISA at 1:312500. ANXA6 antibody can be used for detection of ANXA6 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ANXA6 antibody at -20 °C.

Target Details for ANXA6

Target: ANXA6 (Annexin A6 (ANXA6))

Alternative Name: ANXA6 (ANXA6 Products)

Synonyms: ANX6 antibody, CBP68 antibody, AW107198 antibody, Anx6 antibody, AnxVI antibody, Cabm antibody, Camb antibody, CPB-II antibody, anx6 antibody, cbp68 antibody, ANXA6 antibody, DKFZp459M247 antibody, anxa6 antibody, annexin A6 antibody, annexin A6 L homeolog antibody, ANXA6 antibody, Anxa6 antibody, anxa6 antibody, anxa6.L antibody

Background: Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Exon 21 of annexin VI is alternatively spliced, giving rise to two isoforms that differ by a 6-amino acid insertion at the start of the seventh repeat. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.

Molecular Weight: 74 kDa, 75 kDa

Gene ID: 309

NCBI Accession: NP_001146

UniProt: P08133