PUS1 antibody

Catalog No. ABIN2461496

Product Details anti-PUS1 Antibody

Target: PUS1 (Pseudouridylate Synthase 1 (PUS1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PUS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of mouse PUS1.

Application Details

Application Notes: PUS1 antibody can be used for detection of PUS1 by ELISA at 1:312500. PUS1 antibody can be used for detection of PUS1 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PUS1 antibody at -20 °C.

Target Details for PUS1

Target: PUS1 (Pseudouridylate Synthase 1 (PUS1))

Alternative Name: PUS1 (PUS1 Products)

Synonyms: PUS1 antibody, A730013B20Rik antibody, MPUS1 antibody, mPus1p antibody, MLASA1 antibody, pseudouridylate synthase 1 antibody, pseudouridylate synthase 1, putative antibody, pseudouridine synthase 1 antibody, PUS1 antibody, PVX_093530 antibody, PKH_011400 antibody, Pus1 antibody

Background: Pus1 converts specific uridines to PSI in a number of tRNA substrates. Pus1 acts on positions 27/28 in the anticodon stem and also positions 34 and 36 in the anticodon of an intron containing tRNA. Pus1 is involved in regulation of nuclear receptor activity possibly through pseudouridylation of SRA1 RNA.

Molecular Weight: 43 kDa

Gene ID: 56361

NCBI Accession: NP_001020733

UniProt: Q791J1