DMBX1 antibody

Catalog No. ABIN2461530

Product Details anti-DMBX1 Antibody

Target: DMBX1 (Diencephalon/mesencephalon Homeobox 1 (DMBX1))

Reactivity: Human, Rat, Mouse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DMBX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of mouse DMBX1.

Application Details

Application Notes: DMBX1 antibody can be used for detection of DMBX1 by ELISA at 1:62500. DMBX1 antibody can be used for detection of DMBX1 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store DMBX1 antibody at -20 °C.

Target Details for DMBX1

Target: DMBX1 (Diencephalon/mesencephalon Homeobox 1 (DMBX1))

Alternative Name: DMBX1 (DMBX1 Products)

Synonyms: MBX antibody, OTX3 antibody, PAXB antibody, DMBX1 antibody, Atx antibody, Cdmx antibody, Mbx antibody, Otx3 antibody, mbx2 antibody, zgc:112395 antibody, dmbx1 antibody, mbx antibody, otx3 antibody, pox1 antibody, zMbx1 antibody, diencephalon/mesencephalon homeobox 1 antibody, diencephalon/mesencephalon homeobox 1b antibody, diencephalon/mesencephalon homeobox 1a antibody, DMBX1 antibody, Dmbx1 antibody, dmbx1b antibody, dmbx1a antibody

Background: Transcription factors containing a homeodomain play an important role in the organogenesis of vertebrates. Otx3/Dmbx1 is a member of paired class homeodomain transcription factors. Otx3/Dmbx1 represses the Otx2-mediated transactivation in the developing brain by forming heterodimer with Otx2 on the P3C (TAATCCGATTA) sequence in vitro.

Molecular Weight: 41 kDa

Gene ID: 140477

NCBI Accession: NP_001020738

UniProt: Q91ZK3

Pathways: Feeding Behaviour