ERGIC2 antibody

Catalog No. ABIN2461877

Product Details anti-ERGIC2 Antibody

Target: ERGIC2 (ERGIC and Golgi 2 (ERGIC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERGIC2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ERG Ion Channel 2.

Application Details

Application Notes: ERG Ion Channel 2 antibody can be used for detection of ERG Ion Channel 2 by ELISA at 1:62500. ERG Ion Channel 2 antibody can be used for detection of ERG Ion Channel 2 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ERG Ion Channel 2 antibody at -20 °C.

Target Details for ERGIC2

Target: ERGIC2 (ERGIC and Golgi 2 (ERGIC2))

Abstract: ERGIC2 Products

Synonyms: ptx1 antibody, MGC75899 antibody, zgc:64005 antibody, Erv41 antibody, PTX1 antibody, cd002 antibody, 1200009B18Rik antibody, 4930572C01Rik antibody, AA408438 antibody, Ptx1 antibody, RGD1310606 antibody, ERGIC and golgi 2 antibody, ERGIC and golgi 2 S homeolog antibody, ergic2 antibody, ERGIC2 antibody, ergic2.S antibody, Ergic2 antibody

Background: ERGIon Channel2 possibly play role in transport between endoplasmic reticulum and Golgi. ERGIon Channel2 is downregulated in prostate cancer. ERGIon Channel2 may play an important role in the growth and tumorigenicity of PC-3 prostate tumor cells. Ectopic expression of a partial sequence of ERGIon Channel2 as a VP22-fusion protein in prostate cancer cell line, PC-3, induced cellular senescence. Interferon-beta (IFN-beta) and a number of IFN-inducible genes were upregulated by the ERGIon Channel2-VP22 fusion protein.

Molecular Weight: 43 kDa

Gene ID: 51290

NCBI Accession: NP_057654

UniProt: Q96RQ1