PHAP1 antibody

Catalog No. ABIN2462045

Product Details anti-PHAP1 Antibody

Target: PHAP1 (ANP32A) (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A (ANP32A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHAP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ANP32A.

Application Details

Application Notes: ANP32A antibody can be used for detection of ANP32A by ELISA at 1:312500. ANP32A antibody can be used for detection of ANP32A by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ANP32A antibody at -20 °C.

Target Details for PHAP1

Target: PHAP1 (ANP32A) (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A (ANP32A))

Alternative Name: ANP32A (ANP32A Products)

Synonyms: C15orf1 antibody, HPPCn antibody, I1PP2A antibody, LANP antibody, MAPM antibody, PHAP1 antibody, PHAPI antibody, PP32 antibody, Anp32 antibody, W91701 antibody, pp32 antibody, Anp32a antibody, CG5784 antibody, CT18148 antibody, CT42180 antibody, Dmel\\CG5784 antibody, anon-EST:fe3A2 antibody, wu:fj36e08 antibody, zgc:55516 antibody, ANP32D antibody, acidic nuclear phosphoprotein 32 family member A antibody, acidic (leucine-rich) nuclear phosphoprotein 32 family, member A antibody, CG5784 gene product from transcript CG5784-RB antibody, acidic nuclear phosphoprotein 32 family member A L homeolog antibody, ANP32A antibody, Anp32a antibody, Mapmodulin antibody, anp32a antibody, anp32a.L antibody

Background: ANP32A is a novel potent heat-stable inhibitor protein of protein phosphatase 2A. It may play a key role in self-renewing cell populations where it may act in the nucleus to limit their sensitivity to transformation. Being a tumor suppressor, ANP32A represses cell growth through inhibition of transcription by blocking acetylation and phosphorylation of histone H3 and initiating its proapoptotic activity.

Molecular Weight: 29 kDa

Gene ID: 8125

NCBI Accession: NP_006296

UniProt: P39687