DTX2 antibody
-
- Target See all DTX2 Antibodies
- DTX2 (Deltex Homolog 2 (DTX2))
-
Reactivity
- Human, Dog, Zebrafish (Danio rerio)
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This DTX2 antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA
- Purification
- Antibody is purified by peptide affinity chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DTX2.
- Top Product
- Discover our top product DTX2 Primary Antibody
-
-
- Application Notes
- DTX2 antibody can be used for detection of DTX2 by ELISA at 1:312500. DTX2 antibody can be used for detection of DTX2 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store DTX2 antibody at -20 °C.
-
- Target
- DTX2 (Deltex Homolog 2 (DTX2))
- Alternative Name
- DTX2 (DTX2 Products)
- Synonyms
- RNF58 antibody, 2610524D08Rik antibody, AA408415 antibody, AU022494 antibody, Deltex2 antibody, dtx2 antibody, deltex E3 ubiquitin ligase 2 antibody, probable E3 ubiquitin-protein ligase DTX2 antibody, deltex 2, E3 ubiquitin ligase antibody, deltex 2, E3 ubiquitin ligase S homeolog antibody, DTX2 antibody, Dtx2 antibody, LOC735784 antibody, LOC747633 antibody, dtx2 antibody, dtx2.S antibody
- Background
- DTX2 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. DTX2 probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context and mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. It also functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
- Molecular Weight
- 62 kDa, 67 kDa, 67 kDa, 67 kDa, 93 kDa, 26 kDa, 93 kDa, 45 kDa
- Gene ID
- 113878
- NCBI Accession
- NP_001096066
- UniProt
- Q6XM87
- Pathways
- Notch Signaling
-