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DTX2 antibody

DTX2 Reactivity: Human, Dog, Zebrafish (Danio rerio) WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2462679
  • Target See all DTX2 Antibodies
    DTX2 (Deltex Homolog 2 (DTX2))
    Reactivity
    • 27
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Dog, Zebrafish (Danio rerio)
    Host
    • 24
    • 2
    • 1
    Rabbit
    Clonality
    • 27
    Polyclonal
    Conjugate
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DTX2 antibody is un-conjugated
    Application
    • 25
    • 13
    • 13
    • 7
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), ELISA
    Purification
    Antibody is purified by peptide affinity chromatography method.
    Immunogen
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DTX2.
    Top Product
    Discover our top product DTX2 Primary Antibody
  • Application Notes
    DTX2 antibody can be used for detection of DTX2 by ELISA at 1:312500. DTX2 antibody can be used for detection of DTX2 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    Concentration
    1 mg/mL
    Buffer
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    Handling Advice
    As with any antibody avoid repeat freeze-thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store DTX2 antibody at -20 °C.
  • Target
    DTX2 (Deltex Homolog 2 (DTX2))
    Alternative Name
    DTX2 (DTX2 Products)
    Synonyms
    RNF58 antibody, 2610524D08Rik antibody, AA408415 antibody, AU022494 antibody, Deltex2 antibody, dtx2 antibody, deltex E3 ubiquitin ligase 2 antibody, probable E3 ubiquitin-protein ligase DTX2 antibody, deltex 2, E3 ubiquitin ligase antibody, deltex 2, E3 ubiquitin ligase S homeolog antibody, DTX2 antibody, Dtx2 antibody, LOC735784 antibody, LOC747633 antibody, dtx2 antibody, dtx2.S antibody
    Background
    DTX2 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. DTX2 probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context and mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. It also functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
    Molecular Weight
    62 kDa, 67 kDa, 67 kDa, 67 kDa, 93 kDa, 26 kDa, 93 kDa, 45 kDa
    Gene ID
    113878
    NCBI Accession
    NP_001096066
    UniProt
    Q6XM87
    Pathways
    Notch Signaling
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