NAT2 antibody

Catalog No. ABIN2462790

Product Details anti-NAT2 Antibody

Target: NAT2 (N-Acetyltransferase 2 (Arylamine N-Acetyltransferase) (NAT2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NAT2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NAT2.

Application Details

Application Notes: NAT2 antibody can be used for detection of NAT2 by ELISA at 1:312500. NAT2 antibody can be used for detection of NAT2 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store NAT2 antibody at -20 °C.

Target Details for NAT2

Target: NAT2 (N-Acetyltransferase 2 (Arylamine N-Acetyltransferase) (NAT2))

Alternative Name: NAT2 (NAT2 Products)

Synonyms: AAC2 antibody, NAT-2 antibody, PNAT antibody, AV377607 antibody, Nat2a antibody, NAT antibody, AT-2 antibody, AT-B/AT-II antibody, AT-II antibody, AT2 antibody, N-acetyltransferase 2 antibody, N-acetyltransferase 2 (arylamine N-acetyltransferase) antibody, NAT2 antibody, Nat2 antibody

Background: NAT2 is a N-acetyltransferase 2 (arylamine N-acetyltransferase 2). This enzyme functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in its gene are reponsible for the N-acetylation polymorphism in which human populations segregate into rapid,intermediate, and slow acetylator phenotypes. Polymorphisms in NAT2 are also associated with higher incidences of cancer and drug toxicity.This gene encodes N-acetyltransferase 2 (arylamine N-acetyltransferase 2). This enzyme functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are reponsible for the N-acetylation polymorphism in which human populations segregate into rapid,intermediate, and slow acetylator phenotypes. Polymorphisms in NAT2 are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near NAT2.

Molecular Weight: 32 kDa

Gene ID: 10

NCBI Accession: NP_000006

UniProt: P11245