SWAP70 antibody

Catalog No. ABIN2462957

The Rabbit Polyclonal anti-SWAP70 antibody is suitable to detect SWAP70 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for SWAP70 antibody (ABIN2462957)

Target: SWAP70 (SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SWAP70 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SWAP70 Antibody

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SWAP70.

Application Details

Application Notes: SWAP70 antibody can be used for detection of SWAP70 by ELISA at 1:62500. SWAP70 antibody can be used for detection of SWAP70 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SWAP70 antibody at -20 °C.

Target Details for SWAP70

Target: SWAP70 (SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))

Alternative Name: SWAP70

Background: Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. SWAP70 also mediates signaling of membrane ruffling. It regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.

Molecular Weight: 69 kDa

Gene ID: 23075

NCBI Accession: NP_055870

UniProt: Q9UH65

Pathways: Production of Molecular Mediator of Immune Response