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MBNL2 antibody

MBNL2 Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2463438
  • Target See all MBNL2 Antibodies
    MBNL2 (Muscleblind-Like 2 (MBNL2))
    Reactivity
    • 24
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 23
    • 1
    Rabbit
    Clonality
    • 23
    • 1
    Polyclonal
    Conjugate
    • 14
    • 2
    • 2
    • 2
    • 2
    • 2
    This MBNL2 antibody is un-conjugated
    Application
    • 21
    • 14
    • 14
    • 13
    • 4
    • 1
    Western Blotting (WB), ELISA
    Purification
    Antibody is purified by peptide affinity chromatography method.
    Immunogen
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MBNL2.
    Top Product
    Discover our top product MBNL2 Primary Antibody
  • Application Notes
    MBNL2 antibody can be used for detection of MBNL2 by ELISA at 1:1562500. MBNL2 antibody can be used for detection of MBNL2 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    Concentration
    1 mg/mL
    Buffer
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    Handling Advice
    As with any antibody avoid repeat freeze-thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store MBNL2 antibody at -20 °C.
  • Target
    MBNL2 (Muscleblind-Like 2 (MBNL2))
    Alternative Name
    MBNL2 (MBNL2 Products)
    Synonyms
    1110002M11Rik antibody, AI047808 antibody, AI837313 antibody, AI849185 antibody, AL118326 antibody, MBLL antibody, R75232 antibody, mKIAA4072 antibody, wu:fj89c04 antibody, MBLL39 antibody, PRO2032 antibody, muscleblind like splicing factor 2 antibody, muscleblind-like splicing regulator 2 antibody, muscleblind like splicing regulator 2 antibody, Mbnl2 antibody, mbnl2 antibody, MBNL2 antibody
    Background
    MBNL2 is a C3H-type zinc finger protein, which is similar to the Drosophila melanogaster muscleblind B protein.MBNL2 is a RNA-binding protein that binds to 5'ACACCC-3' core sequence. It binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs. MBNL2 seems to regulate expression and localization of ITGA3 by transporting it from the nucleus to cytoplasm. It may play a role in myotonic dystrophy pathophysiology (DM).
    Molecular Weight
    28 kDa
    Gene ID
    10150
    NCBI Accession
    NP_005748
    UniProt
    O95205
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