PAXIP1 antibody
-
- Target See all PAXIP1 Antibodies
- PAXIP1 (PAX Interacting (With Transcription-Activation Domain) Protein 1 (PAXIP1))
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This PAXIP1 antibody is un-conjugated
-
Application
- ELISA, Western Blotting (WB)
- Purification
- Antibody is purified by peptide affinity chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PAXIP1.
- Top Product
- Discover our top product PAXIP1 Primary Antibody
-
-
- Application Notes
- PAXIP1 antibody can be used for detection of PAXIP1 by ELISA at 1:62500. PAXIP1 antibody can be used for detection of PAXIP1 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store PAXIP1 antibody at -20 °C.
-
- Target
- PAXIP1 (PAX Interacting (With Transcription-Activation Domain) Protein 1 (PAXIP1))
- Alternative Name
- PAXIP1 (PAXIP1 Products)
- Synonyms
- CAGF29 antibody, PACIP1 antibody, PAXIP1L antibody, PTIP antibody, TNRC2 antibody, wu:fa04b06 antibody, zgc:92593 antibody, cagf28 antibody, cagf29 antibody, k14 antibody, pacip1 antibody, paxip1l antibody, ptip antibody, tnrc2 antibody, D5Ertd149e antibody, PAX interacting protein 1 antibody, PAX interacting (with transcription-activation domain) protein 1 antibody, PAX interacting protein 1 L homeolog antibody, PAXIP1 antibody, paxip1 antibody, paxip1.L antibody, Paxip1 antibody
- Background
- PAXIP1 functions as a key component of the DNA damage response, and phosphoserine or phosphothreonine-specific binding modules. PAXIP1 recognizes substrates phosphorylated by the kinases ataxia telangiectasia-mutated (ATM), ataxia telangiectasia and RAD3-related (ATR) in response to gamma irradiation. It may play a role in PAX2-dependent transcriptional regulation. PAXIP1 plays a role in early development, most probably in cell proliferation.
- Molecular Weight
- 74 kDa
- Gene ID
- 22976
- UniProt
- Q6ZW49
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
-