CCDC50 antibody

Catalog No. ABIN2463552

Product Details anti-CCDC50 Antibody

Target: CCDC50 (Coiled-Coil Domain Containing 50 (CCDC50))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC50 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CCDC50.

Application Details

Application Notes: CCDC50 antibody can be used for detection of CCDC50 by ELISA at 1:1562500. CCDC50 antibody can be used for detection of CCDC50 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CCDC50 antibody at -20 °C.

Target Details for CCDC50

Target: CCDC50 (Coiled-Coil Domain Containing 50 (CCDC50))

Alternative Name: CCDC50 (CCDC50 Products)

Synonyms: ymer antibody, C3orf6 antibody, DFNA44 antibody, YMER antibody, 2610529H08Rik antibody, 5730448P06Rik antibody, AW048328 antibody, AW546090 antibody, D16Bwg1543e antibody, C3orf6h antibody, c3orf6 antibody, coiled-coil domain containing 50 antibody, coiled-coil domain containing 50 L homeolog antibody, CCDC50 antibody, ccdc50.L antibody, ccdc50 antibody, Ccdc50 antibody

Background: CCDC50 is a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling.

Molecular Weight: 56 kDa

Gene ID: 152137

NCBI Accession: NP_848018

UniProt: Q8IVM0