STAG3 antibody

Catalog No. ABIN2463593

Product Details anti-STAG3 Antibody

Target: STAG3 (Stromal Antigen 3 (STAG3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAG3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human STAG3.

Application Details

Application Notes: STAG3 antibody can be used for detection of STAG3 by ELISA at 1:62500. STAG3 antibody can be used for detection of STAG3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store STAG3 antibody at -20 °C.

Target Details for STAG3

Target: STAG3 (Stromal Antigen 3 (STAG3))

Alternative Name: STAG3 (STAG3 Products)

Synonyms: STAG3 antibody, SA-2 antibody, stromal antigen 3 antibody, STAG3 antibody, stag3 antibody, Stag3 antibody

Background: STAG3 is a meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I.

Molecular Weight: 135 kDa

Gene ID: 10734

NCBI Accession: NP_036579

UniProt: Q9UJ98