ATG16L1 antibody

Catalog No. ABIN2463625

Product Details anti-ATG16L1 Antibody

Target: ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATG16L1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ATG16L1.

Application Details

Application Notes: ATG16L1 antibody can be used for detection of ATG16L1 by ELISA at 1:1562500. ATG16L1 antibody can be used for detection of ATG16L1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ATG16L1 antibody at -20 °C.

Target Details for ATG16L1

Target: ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))

Alternative Name: ATG16L1 (ATG16L1 Products)

Synonyms: APG16L antibody, ATG16A antibody, ATG16L antibody, IBD10 antibody, WDR30 antibody, 1500009K01Rik antibody, Apg16l antibody, Atg16l antibody, Wdr30 antibody, atg16 antibody, atg16l antibody, fb57e05 antibody, wu:fb57e05 antibody, zgc:110147 antibody, autophagy related 16 like 1 antibody, autophagy related 16-like 1 (S. cerevisiae) antibody, autophagy related 16-like 1 antibody, autophagy related 16 like 1 S homeolog antibody, ATG16 autophagy related 16-like 1 (S. cerevisiae) antibody, ATG16L1 antibody, Atg16l1 antibody, atg16l1 antibody, atg16l1.S antibody

Background: Autophagy is the major intracellular degradation system delivering cytoplasmic components to lysosomes, and it accounts for degradation of most long-lived proteins and some organelles. Cytoplasmic constituents, including organelles, are sequestered into double-membraned autophagosomes, which subsequently fuse with lysosomes. ATG16L1 is a component of a large protein complex essential for autophagy.Autophagy is the major intracellular degradation system delivering cytoplasmic components to lysosomes, and it accounts for degradation of most long-lived proteins and some organelles. Cytoplasmic constituents, including organelles, are sequestered into double-membraned autophagosomes, which subsequently fuse with lysosomes. ATG16L1 is a component of a large protein complex essential for autophagy (Mizushima et al., 2003 [PubMed 12665549]).

Molecular Weight: 66 kDa

Gene ID: 55054

NCBI Accession: NP_060444

UniProt: Q676U5

Pathways: Autophagy