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NLRP3 antibody (C-Term)

NLRP3 Reactivity: Human ELISA, FACS Host: Goat Polyclonal unconjugated
Catalog No. ABIN2465561
  • Target See all NLRP3 Antibodies
    NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))
    Binding Specificity
    • 16
    • 10
    • 8
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 83
    • 44
    • 32
    • 17
    • 4
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 79
    • 11
    • 2
    • 1
    Goat
    Clonality
    • 77
    • 16
    Polyclonal
    Conjugate
    • 45
    • 9
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NLRP3 antibody is un-conjugated
    Application
    • 62
    • 37
    • 17
    • 13
    • 13
    • 13
    • 11
    • 10
    • 8
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS)
    Purification
    Cryopyrin antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
    Immunogen
    Cryopyrin antibody was raised against a 13 amino acid synthetic peptide near the C-Terminus of Cryopyrin.
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  • Application Notes
    ELISA: Antibody detection limit dilution >1:32000. Western Blot: No signal obtained yet but low background observed in Daudi, A431, Jurkat, U937 and MOLT-4 lysates at up to 1 μg/mL.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    500 μg/mL
    Buffer
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Minimize freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Aliquot and store at -20 °C.
  • Target
    NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))
    Alternative Name
    Cryopyrin (NLRP3 Products)
    Gene ID
    114548
    NCBI Accession
    NP_004886
    UniProt
    Q96P20
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Inflammasome
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