BAI1 antibody (N-Term)

Catalog No. ABIN2469439

This Rabbit Polyclonal antibody specifically detects BAI1 in IHC and ELISA. It exhibits reactivity toward Human, Monkey, Cow, Gibbon and Gorilla.

Quick Overview for BAI1 antibody (N-Term) (ABIN2469439)

Target: BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))

Reactivity: Human, Monkey, Cow, Gibbon, Gorilla

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAI1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-BAI1 Antibody

Binding Specificity: N-Term

Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Purification: Immunoaffinity Chromatography

Immunogen: BAI1 antibody was raised against a peptide located in the N-Terminal domain of BAI1 (Human).

Application Details

Application Notes: BAI1 antibody can be used in immunohistochemistry starting at 10 - 15 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-80 °C

Storage Comment: BAI1 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Target Details for BAI1

Target: BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))

Alternative Name: BAI1

Background: BAI1 is an Orphan-B GPCR with an unknown ligand. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis, and a growth suppressor of glioblastoma. Along with BAI1, there are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3, which have similar tissue specificities and structures. However, only BAI1 is transcriptionally regulated by p53. Loss of BAI1 expression has been implicated in glioblastoma.

Gene ID: 575

UniProt: O14514

Pathways: p53 Signaling