BACE1 antibody (Internal Region)
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- Target See all BACE1 Antibodies
- BACE1 (Beta-secretase 1 (BACE1))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Monkey, Pig, Bat, Hamster, Gibbon
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This BACE1 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC)
- Specificity
- BLAST analysis of the peptide immunogen showed no homology with other human proteins.
- Purification
- Immunoaffinity Chromatography
- Immunogen
- BACE1 antibody was raised against a peptide located near the internal domain of BACE1 (Human).
- Top Product
- Discover our top product BACE1 Primary Antibody
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- Application Notes
- BACE1 antibody can be used in immunohistochemistry starting at 1:50.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, 0.1 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- As with all antibodies avoid freeze/thaw cycles.
- Storage
- 4 °C/-80 °C
- Storage Comment
- BACE1 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
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- Target
- BACE1 (Beta-secretase 1 (BACE1))
- Alternative Name
- BACE1 (BACE1 Products)
- Synonyms
- ASP2 antibody, BACE antibody, HSPC104 antibody, C76936 antibody, Bace antibody, MGC145931 antibody, BACE1 antibody, zgc:77409 antibody, beta-secretase 1 antibody, beta-site APP cleaving enzyme 1 antibody, beta-site APP-cleaving enzyme 1 antibody, BACE1 antibody, Bace1 antibody, bace1 antibody
- Background
- Bace 1 is responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
- Gene ID
- 23621
- UniProt
- P56817
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