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BACE1 antibody (Internal Region)

BACE1 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Monkey, Pig, Bat, Hamster, Gibbon IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2469509
  • Target See all BACE1 Antibodies
    BACE1 (Beta-secretase 1 (BACE1))
    Binding Specificity
    • 16
    • 13
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 78
    • 49
    • 39
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Monkey, Pig, Bat, Hamster, Gibbon
    Host
    • 72
    • 10
    Rabbit
    Clonality
    • 69
    • 13
    Polyclonal
    Conjugate
    • 51
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BACE1 antibody is un-conjugated
    Application
    • 62
    • 36
    • 28
    • 17
    • 13
    • 13
    • 12
    • 10
    • 9
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    Immunohistochemistry (IHC)
    Specificity
    BLAST analysis of the peptide immunogen showed no homology with other human proteins.
    Purification
    Immunoaffinity Chromatography
    Immunogen
    BACE1 antibody was raised against a peptide located near the internal domain of BACE1 (Human).
    Top Product
    Discover our top product BACE1 Primary Antibody
  • Application Notes
    BACE1 antibody can be used in immunohistochemistry starting at 1:50.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, 0.1 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    As with all antibodies avoid freeze/thaw cycles.
    Storage
    4 °C/-80 °C
    Storage Comment
    BACE1 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
  • Target
    BACE1 (Beta-secretase 1 (BACE1))
    Alternative Name
    BACE1 (BACE1 Products)
    Synonyms
    ASP2 antibody, BACE antibody, HSPC104 antibody, C76936 antibody, Bace antibody, MGC145931 antibody, BACE1 antibody, zgc:77409 antibody, beta-secretase 1 antibody, beta-site APP cleaving enzyme 1 antibody, beta-site APP-cleaving enzyme 1 antibody, BACE1 antibody, Bace1 antibody, bace1 antibody
    Background
    Bace 1 is responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
    Gene ID
    23621
    UniProt
    P56817
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