Integrin beta 2 antibody (AA 534-546)

Catalog No. ABIN2470788

The Mouse Monoclonal anti-Integrin beta 2 antibody (Clone MEM-48) (ABIN2470788) specifically detects Integrin beta 2 in FACS, WB, IP and IHC. The antibody is reactive with Human samples.

Quick Overview for Integrin beta 2 antibody (AA 534-546) (ABIN2470788)

Target: Integrin beta 2 (ITGB2)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Integrin beta 2 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)

Clone: MEM-48

Product Details anti-Integrin beta 2 Antibody

Binding Specificity: AA 534-546

Specificity: Recognizes an epitope involving residues 534-546 in cysteine-rich repeat 3 of the CD18 antigen (integrin beta2 subunit, beta2 integrin) . CD18 is a 90-95 kD type I transmembrane protein expressed on all leukocytes.

Purification: Protein A Column

Immunogen: Leukocytes of a patient suffering from a LGL-type leukemia

Isotype: IgG1

Application Details

Application Notes: CD18 antibody can be used in Western Blot starting at 1 - 3 μg/mL, and immunohistochemistry starting at 5 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate buffered saline (PBS), approx. pH 7.4, 0.2 m filter sterilized

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: CD18 antibody can be stored short term 4 °C. For long term storage aliquot and store at -20 °C.

Target Details for Integrin beta 2

Target: Integrin beta 2 (ITGB2)

Alternative Name: CD18

Gene ID: 3689

UniProt: P05107

Pathways: NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation