SH2B3 antibody (SH2B Adaptor Protein 3) (N-Term)

Details for Product anti-SH2B3 Antibody No. ABIN2475350
Antigen
  • LNK
  • IDDM20
  • AI429800
  • Lnk
  • SH2B adaptor protein 3
  • SH2B3
  • Sh2b3
Epitope
N-Term
8
3
2
2
1
1
1
Reactivity
Human
62
24
23
2
Host
Goat
39
16
8
Clonality
Polyclonal
Conjugate
This SH2B3 antibody is un-conjugated
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
46
17
13
13
12
7
5
2
1
1
Options
Isotype IgG
Characteristics Purified IgG
Purification Purified
Plasmids, Primers & others Plasmids, Primers & others SH2B3 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name LNK (SH2B3 Antibody Abstract)
Background Synonyms: LYMPHOCYTE ADAPTOR PROTEIN
Gene ID 10019
UniProt Q9UQQ2
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Supplier Images
Image no. 1 for anti-SH2B Adaptor Protein 3 (SH2B3) (N-Term) antibody (ABIN2475350) anti-SH2B Adaptor Protein 3 (SH2B3) (N-Term) antibody
Product cited in: Gery, Gueller, Chumakova, Kawamata, Liu, Koeffler: "Adaptor protein Lnk negatively regulates the mutant MPL, MPLW515L associated with myeloproliferative disorders." in: Blood, Vol. 110, Issue 9, pp. 3360-4, 2007 (PubMed).

Fitau, Boulday, Coulon, Quillard, Charreau: "The adaptor molecule Lnk negatively regulates tumor necrosis factor-alpha-dependent VCAM-1 expression in endothelial cells through inhibition of the ERK1 and -2 pathways." in: The Journal of biological chemistry, Vol. 281, Issue 29, pp. 20148-59, 2006 (PubMed).

Tong, Lodish: "Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis." in: The Journal of experimental medicine, Vol. 200, Issue 5, pp. 569-80, 2004 (PubMed).

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