GRIN2B antibody (pTyr1472)

Catalog No. ABIN2475893

There are 2+ publications for this product available. The Rabbit Polyclonal anti-GRIN2B antibody is suitable to detect GRIN2B in samples from Human, Rat, Mouse, Dog, Cow, Chicken, Zebrafish (Danio rerio) and Monkey. It has been validated for WB.

Quick Overview for GRIN2B antibody (pTyr1472) (ABIN2475893)

Target: GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

Reactivity: Human, Rat, Mouse, Dog, Cow, Chicken, Zebrafish (Danio rerio), Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRIN2B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GRIN2B Antibody

Binding Specificity: pTyr1472

Cross-Reactivity: Chicken, Cow (Bovine), Dog (Canine), Human, Monkey, Mouse (Murine), Zebrafish

Characteristics: Purified IgG

Purification: Purified

Immunogen: Synthetic phosphopeptide corresponding to an amino acid sequence within the NR2B subunit of the NMDA receptor, which includes phosphorylated Tyr1472.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

References for anti-GRIN2B antibody (ABIN2475893)

Popke: "From anticholinesterase toxicity to Alzheimer's disease: important interactions of cholinergic and NMDA receptor systems." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 72, Issue 2, pp. 185-7, (2003) (PubMed).

Takasu, Dalva, Zigmond, Greenberg: "Modulation of NMDA receptor-dependent calcium influx and gene expression through EphB receptors." in: Science (New York, N.Y.), Vol. 295, Issue 5554, pp. 491-5, (2002) (PubMed).

Target Details for GRIN2B

Target: GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

Alternative Name: Nmdar Nr2b

Gene ID: 24410

UniProt: Q00960

Pathways: Response to Growth Hormone Stimulus, Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity