TNF alpha antibody

Catalog No. ABIN2476875

Cited in 3+ publications. The Rabbit Polyclonal anti-TNF alpha antibody (ABIN2476875) specifically detects TNF alpha in WB, ELISA and Func. The antibody is reactive with Mouse samples.

Quick Overview for TNF alpha antibody (ABIN2476875)

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNF alpha antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Functional Studies (Func)

Product Details anti-TNF alpha Antibody

Characteristics: Purified IgG

Purification: Purified

Immunogen: Recombinant mouse TNF&alpha, (PMP24)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 1.0 mg/mL

References for anti-TNF alpha antibody (ABIN2476875)

van Horssen, Ten Hagen, Eggermont: "TNF-alpha in cancer treatment: molecular insights, antitumor effects, and clinical utility." in: The oncologist, Vol. 11, Issue 4, pp. 397-408, (2006) (PubMed).

Schäfers, Geis, Brors, Yaksh, Sommer: "Anterograde transport of tumor necrosis factor-alpha in the intact and injured rat sciatic nerve." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 22, Issue 2, pp. 536-45, (2002) (PubMed).

Khaskhely, Maruno, Uezato, Takamiyagi, Ramzi, Al-Kasem, Kariya, Toda, Hashiguchi, Gomez Landires, Nonaka: "Low-dose UVB contributes to host resistance against Leishmania amazonensis infection in mice through induction of gamma interferon and tumor necrosis factor alpha cytokines." in: Clinical and diagnostic laboratory immunology, Vol. 9, Issue 3, pp. 677-86, (2002) (PubMed).

Target Details for TNF alpha

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Alternative Name: TNF alpha

Gene ID: 21926

UniProt: P06804

Pathways: NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome