GDF2 antibody (AA 87-98)

Catalog No. ABIN2477688

The Rabbit Polyclonal anti-GDF2 antibody (ABIN2477688) specifically detects GDF2 in WB, ELISA, IHC (p) and IF. The antibody is reactive with Human samples.

Quick Overview for GDF2 antibody (AA 87-98) (ABIN2477688)

Target: GDF2 (Growth Differentiation Factor 2 (GDF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GDF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Product Details anti-GDF2 Antibody

Binding Specificity: AA 87-98

Specificity: This antibody recognises Human BMP9 (Bone Morphogenic Protein), a member of the TGF-beta superfamily.BMPs act through binding with a receptor complex consisting of type I and type II serine/threonine kinases, resulting ultimately in the activation of the Smad protein and mitogen-activated protein kinase (MAPK) signaling pathways. Several antagonist proteins, including, noggin, chordin, gremlin and follistatin, are responsible for modulating the signaling effects of BMPs, through the binding and blocking of receptor ligands, thereby preventing activation.

Characteristics: Purified IgG

Purification: Purified

Immunogen: Synthetic peptide corresponding to the amino acids 87-98 of the native molecule conjugated to keyhole limpet haemocyanin.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 5.0 mg/mL

Target Details for GDF2

Target: GDF2 (Growth Differentiation Factor 2 (GDF2))

Alternative Name: BMP-9

Background: Synonyms: GROWTH DIFFERENTIATION FACTOR 2

Gene ID: 2658

UniProt: Q9UK05

Pathways: Transition Metal Ion Homeostasis