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Integrin beta 2 antibody (Activation Site)

ITGB2 Reactivity: Human FACS, WB, IP Host: Mouse Monoclonal MEM-148 unconjugated
Catalog No. ABIN2478861
  • Target See all Integrin beta 2 (ITGB2) Antibodies
    Integrin beta 2 (ITGB2)
    Binding Specificity
    • 19
    • 15
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Activation Site
    Reactivity
    • 193
    • 54
    • 45
    • 10
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 100
    • 89
    • 36
    • 2
    • 1
    • 1
    Mouse
    Clonality
    • 134
    • 90
    • 2
    Monoclonal
    Conjugate
    • 102
    • 23
    • 21
    • 16
    • 8
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Integrin beta 2 antibody is un-conjugated
    Application
    • 132
    • 82
    • 52
    • 45
    • 39
    • 32
    • 29
    • 26
    • 26
    • 26
    • 22
    • 12
    • 9
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP)
    Specificity
    Specificity property: activation epitope
    Characteristics
    Purified IgG
    Purification
    Purified
    Clone
    MEM-148
    Isotype
    IgG1
    Top Product
    Discover our top product ITGB2 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/mL
    Preservative
    Without preservative
  • Feng, Zhang, Almulki, Faez, Whitford, Hafezi-Moghadam, Cross: "Endogenous PMN sialidase activity exposes activation epitope on CD11b/CD18 which enhances its binding interaction with ICAM-1." in: Journal of leukocyte biology, Vol. 90, Issue 2, pp. 313-21, (2011) (PubMed).

    Luissint, Lutz, Calderwood, Couraud, Bourdoulous: "JAM-L-mediated leukocyte adhesion to endothelial cells is regulated in cis by alpha4beta1 integrin activation." in: The Journal of cell biology, Vol. 183, Issue 6, pp. 1159-73, (2008) (PubMed).

    Drbal, Angelisová, Hilgert, Cerný, Novák, Horejsí: "A proteolytically truncated form of free CD18, the common chain of leukocyte integrins, as a novel marker of activated myeloid cells." in: Blood, Vol. 98, Issue 5, pp. 1561-6, (2001) (PubMed).

  • Target
    Integrin beta 2 (ITGB2)
    Alternative Name
    CD18 (ITGB2 Products)
    Background
    Synonyms: INTEGRIN BETA 2 CHAIN
    Gene ID
    3689
    UniProt
    P05107
    Pathways
    NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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