Integrin beta 2 antibody (Activation Site)
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- Target See all Integrin beta 2 (ITGB2) Antibodies
- Integrin beta 2 (ITGB2)
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Binding Specificity
- Activation Site
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Integrin beta 2 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP)
- Specificity
- Specificity property: activation epitope
- Characteristics
- Purified IgG
- Purification
- Purified
- Clone
- MEM-148
- Isotype
- IgG1
- Top Product
- Discover our top product ITGB2 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Preservative
- Without preservative
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Endogenous PMN sialidase activity exposes activation epitope on CD11b/CD18 which enhances its binding interaction with ICAM-1." in: Journal of leukocyte biology, Vol. 90, Issue 2, pp. 313-21, (2011) (PubMed).
: "JAM-L-mediated leukocyte adhesion to endothelial cells is regulated in cis by alpha4beta1 integrin activation." in: The Journal of cell biology, Vol. 183, Issue 6, pp. 1159-73, (2008) (PubMed).
: "A proteolytically truncated form of free CD18, the common chain of leukocyte integrins, as a novel marker of activated myeloid cells." in: Blood, Vol. 98, Issue 5, pp. 1561-6, (2001) (PubMed).
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Endogenous PMN sialidase activity exposes activation epitope on CD11b/CD18 which enhances its binding interaction with ICAM-1." in: Journal of leukocyte biology, Vol. 90, Issue 2, pp. 313-21, (2011) (PubMed).
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- Target
- Integrin beta 2 (ITGB2)
- Alternative Name
- CD18 (ITGB2 Products)
- Background
- Synonyms: INTEGRIN BETA 2 CHAIN
- Gene ID
- 3689
- UniProt
- P05107
- Pathways
- NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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