Integrin beta 2 antibody (Activation Site)
Quick Overview for Integrin beta 2 antibody (Activation Site) (ABIN2478861)
Target
See all Integrin beta 2 (ITGB2) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- Activation Site
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Specificity
- Specificity property: activation epitope
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Characteristics
- Purified IgG
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Purification
- Purified
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Isotype
- IgG1
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.0 mg/mL
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Preservative
- Without preservative
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Endogenous PMN sialidase activity exposes activation epitope on CD11b/CD18 which enhances its binding interaction with ICAM-1." in: Journal of leukocyte biology, Vol. 90, Issue 2, pp. 313-21, (2011) (PubMed).
: "JAM-L-mediated leukocyte adhesion to endothelial cells is regulated in cis by alpha4beta1 integrin activation." in: The Journal of cell biology, Vol. 183, Issue 6, pp. 1159-73, (2008) (PubMed).
: "A proteolytically truncated form of free CD18, the common chain of leukocyte integrins, as a novel marker of activated myeloid cells." in: Blood, Vol. 98, Issue 5, pp. 1561-6, (2001) (PubMed).
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Endogenous PMN sialidase activity exposes activation epitope on CD11b/CD18 which enhances its binding interaction with ICAM-1." in: Journal of leukocyte biology, Vol. 90, Issue 2, pp. 313-21, (2011) (PubMed).
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- Integrin beta 2 (ITGB2)
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Alternative Name
- CD18
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Background
- Synonyms: INTEGRIN BETA 2 CHAIN
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Gene ID
- 3689
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UniProt
- P05107
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Pathways
- NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
Target
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