TRPM7 antibody (AA 1817-1863) (PE)
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- Target See all TRPM7 Antibodies
- TRPM7 (Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7))
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Binding Specificity
- AA 1817-1863
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Reactivity
- Mouse
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This TRPM7 antibody is conjugated to PE
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Antibody Array (AA)
- Specificity
- Detects ~220 kDa in extracts of cells transiently transfected with TrpM7. No cross-reactivity against TrpM6.
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Protein G Purified
- Immunogen
- Fusion protein amino acids 1817-1863 (C- terminus) of mouse TrpM7
- Clone
- S74
- Isotype
- IgG1
- Top Product
- Discover our top product TRPM7 Primary Antibody
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- Application Notes
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- WB (1:1000)
- IHC (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- Comment
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1 μg/ml of ABIN2483119 was sufficient for detection of TrpM7 in 10 μg of COS cell lysate transiently transfected with TprM7 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Conjugated antibodies should be stored at 4°C
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- Target
- TRPM7 (Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7))
- Alternative Name
- TRPM7 (TRPM7 Products)
- Synonyms
- cb495 antibody, TRPM7 antibody, chak antibody, chak1 antibody, ltrpc7 antibody, trp-plik antibody, ALSPDC antibody, CHAK antibody, CHAK1 antibody, LTRPC7 antibody, TRP-PLIK antibody, 2310022G15Rik antibody, 4833414K03Rik antibody, 5033407O22Rik antibody, LTrpC-7 antibody, Ltpr7 antibody, Ltrpc7 antibody, TRPPLIK antibody, Chak antibody, Trp-plik antibody, transient receptor potential cation channel subfamily M member 7 antibody, transient receptor potential cation channel, subfamily M, member 7 antibody, TRPM7 antibody, trpm7 antibody, Trpm7 antibody
- Background
- TRPs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants (1, 2).
- Gene ID
- 58800
- NCBI Accession
- NP_001157797
- UniProt
- Q923J1
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