Fc gamma RII (CD32) (pTyr292) antibody

Catalog No. ABIN2567567

Product Details

Target: Fc gamma RII (CD32)

Binding Specificity: pTyr292

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Specificity: The antibody detects endogenous levels of CD32 only when phosphorylated at tyrosine 292.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: CD32 (phospho Tyr292) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 292 (I-T-Y (p)-S-L) derived from Human CD32.

Isotype: IgG

Application Details

Application Notes: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store antibody at -20°C for up to one year.

Target Details

Target: Fc gamma RII (CD32)

Alternative Name: CD32 (CD32 Products)

Synonyms: CD32 antibody, CD32B antibody, FCG2 antibody, FCGR2 antibody, IGFR2 antibody, FCGR2B antibody, AI528646 antibody, F630109E10Rik antibody, Fc[g]RII antibody, FcgRII antibody, Fcgr2 antibody, Fcgr2a antibody, Fcr-2 antibody, Fcr-3 antibody, Ly-17 antibody, Ly-m20 antibody, LyM-1 antibody, Lym-1 antibody, FCRII antibody, FcRII antibody, Fc fragment of IgG receptor IIb antibody, Fc receptor, IgG, low affinity IIb antibody, FCGR2B antibody, Fcgr2b antibody

Background: Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.

Molecular Weight: 32 kDa

Gene ID: 2213

NCBI Accession: NP_003992

UniProt: P31994