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CD40 antibody (FITC)

CD40 Reactivity: Human FACS Host: Mouse Monoclonal 5C3 FITC

Catalog No. ABIN2567685

Datasheet as PDF

Target See all CD40 Antibodies

CD40
Reactivity
188

97

20

20

7

6

4

4

4

4

2

2

2

2

2

1

1
Human
Host
103

100

43

3

1

1

1
Mouse
Compatible Secondaries
Clonality
156

89

5
Monoclonal
Conjugate
119

22

20

20

12

6

5

4

3

3

3

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD40 antibody is conjugated to FITC
Application
145

92

62

50

30

28

19

18

17

14

13

13

5

4

4

4

3

3

3

3

3

2

2

2

2

2

1

1
Flow Cytometry (FACS)

Specificity

The 5C3 monoclonal antibody specifically reacts with human CD40, a 48kDA type I glycoprotein.

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Clone

5C3

Isotype

IgG1 kappa

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anti-CD40 (CD40) antibody
CD40 Reactivity: Human FACS, IHC, IF, StM, DNA Mic Host: Mouse Monoclonal C40-1605 unconjugated

anti-CD40 (CD40) antibody
CD40 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-CD40 (CD40) (C-Term) antibody
CD40 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-CD40 (CD40) (AA 21-193) antibody
CD40 Reactivity: Human FACS, WB, ELISA, IHC, ICC, Neut Host: Mouse Monoclonal 4E1B9 unconjugated

anti-CD40 (CD40) (AA 29-107) antibody
CD40 Reactivity: Human FACS, ELISA, IHC, StM, Coat Host: Mouse Monoclonal C40-2383 unconjugated

anti-CD40 (CD40) (Extracellular Domain) antibody
CD40 Reactivity: Human FACS, IHC, St Host: Mouse Monoclonal 5C3 unconjugated

anti-CD40 (CD40) (AA 1-360) antibody
CD40 Reactivity: Human, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-CD40 (CD40) antibody (FITC)
CD40 Reactivity: Human FACS Host: Mouse Monoclonal HI40a FITC

anti-CD40 (CD40) antibody
CD40 Reactivity: Human FACS, IHC, IP, Act Host: Rabbit Chimeric G28-5 unconjugated Recombinant Antibody

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Format

Liquid

Buffer

Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Storage

4 °C

Storage Comment

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Target

CD40

Alternative Name

CD40 (CD40 Products)

Synonyms

Bp50 antibody, CDW40 antibody, TNFRSF5 antibody, p50 antibody, AI326936 antibody, GP39 antibody, HIGM1 antibody, IGM antibody, IMD3 antibody, T-BAM antibody, TRAP antibody, Tnfrsf5 antibody, TNFSF5 antibody, CD40 molecule antibody, CD40 antigen antibody, CD40 antibody, Cd40 antibody

Background

The 5C3 monoclonal antibody specifically reacts with human CD40, a 48kDA type I glycoprotein. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The 5C3 antibody partially blocks the binding of CD40L (CD154). In the presence of IL-4 or PMA, the 5C3 antibody promotes B cell proliferation.

Gene ID

958

UniProt

P25942

Pathways

NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints