Claudin 3 antibody (pTyr219)

Catalog No. ABIN2568077

Product Details anti-Claudin 3 Antibody

Target: Claudin 3 (CLDN3)

Binding Specificity: pTyr219

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 3 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: The antibody detects endogenous levels of Claudin 3 only when phosphorylated at tyrosine 219.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: Claudin 3 (phospho Tyr219) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 219 (R-K-D-Y (p)-V) derived from Human Claudin 3.

Isotype: IgG

Application Details

Application Notes: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store antibody at -20°C for up to one year.

Target Details for Claudin 3

Target: Claudin 3 (CLDN3)

Alternative Name: Claudin 3 (CLDN3 Products)

Synonyms: claudin-3 antibody, cpe-r2 antibody, cpetr2 antibody, hrvp1 antibody, rvp1 antibody, CLDN3 antibody, LOC100228090 antibody, C7orf1 antibody, CPE-R2 antibody, CPETR2 antibody, HRVP1 antibody, RVP1 antibody, AI182374 antibody, Cpetr2 antibody, mRVP1 antibody, claudin 3 L homeolog antibody, claudin 3 antibody, claudin-4-like antibody, cldn3.L antibody, cldn3 antibody, CLDN3 antibody, LOC100228090 antibody, Cldn3 antibody

Background: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands.

Molecular Weight: 28 kDa

Gene ID: 1365

NCBI Accession: NP_001297

UniProt: O15551

Pathways: Hepatitis C