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HCLS1 antibody (pTyr397)
HCLS1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-HCLS1 Antibody
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Target
See all HCLS1 Antibodies
HCLS1
(Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1))
Binding Specificity
All epitopes for HCLS1 antibodies
pTyr397
Reactivity
All reactivities for HCLS1 antibodies
Human
Host
All hosts for HCLS1 antibodies
Rabbit
Clonality
All clonalities for HCLS1 antibodies
Polyclonal
Conjugate
All conjugates for HCLS1 antibodies
This HCLS1 antibody is un-conjugated
Application
All applications for HCLS1 antibodies
Western Blotting (WB)
Specificity
The antibody detects endogenous levels of HS1 only when phosphorylated at tyrosine 397.
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Immunogen
HS1 (phospho Tyr397) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 397 (G-D-Y (p)-E-E) derived from Human HS1 .
Isotype
IgG
Top Product
Discover our top product HCLS1 Primary Antibody
Alternatives
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anti-Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1) (AA 28-77) antibody
HCLS1
Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig, Pig
WB, IHC, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
Western Blot: 1:500~1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store antibody at -20°C for up to one year.
Target Details for HCLS1
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Target
HCLS1
(Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1))
Alternative Name
HS1 (HCLS1 Products )
Synonyms
CTTNL antibody, HS1 antibody, AW213261 antibody, HCLS1 antibody, hcls1 antibody, si:dkey-9a20.6 antibody, wu:fk96b08 antibody, zgc:154014 antibody, hematopoietic cell-specific Lyn substrate 1 antibody, hematopoietic cell specific Lyn substrate 1 antibody, hematopoietic lineage cell-specific protein-like antibody, HCLS1 antibody, Hcls1 antibody, LOC100223649 antibody, hcls1 antibody
Background
Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. Directly associates with HAX-1, through binding to its C-terminal region. May also be involved in the regulation of gene expression.
Molecular Weight
54 kDa
Gene ID
3059
NCBI Accession
NP_005326
UniProt
P14317
Pathways
Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Regulation of Actin Filament Polymerization , Myometrial Relaxation and Contraction , Maintenance of Protein Location
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