IKK-alpha /IKK-beta antibody (pSer180, pSer181)

Catalog No. ABIN2568224

Product Details anti-IKK-alpha /IKK-beta Antibody

Target: IKK-alpha /IKK-beta

Binding Specificity: pSer180, pSer181

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IKK-alpha /IKK-beta antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: The antibody detects endogenous level of IKK- alpha/beta only when phosphorylated at serine 180/181.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: IKK- alpha/ beta (phospho Ser180/181) antibody was raised against a peptide sequence around phosphorylation site of serine 180/181 (C-T-S (p)-F-V) derived from Human IKK- alpha/ beta.

Isotype: IgG

Application Details

Application Notes: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store antibody at -20°C for up to one year.

Target Details for IKK-alpha /IKK-beta

Target: IKK-alpha /IKK-beta

Alternative Name: IKK alpha/ beta (IKK-alpha /IKK-beta Products)

Background: Acts as part of the IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Also phosphorylates NCOA3.

Molecular Weight: 85 kDa

Gene ID: 1147

NCBI Accession: NP_001269

UniProt: O15111, O14920