Protein Tob1 (TOB1) (pSer164) antibody
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- Target See all Protein Tob1 (TOB1) Antibodies
- Protein Tob1 (TOB1)
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Binding Specificity
- pSer164
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- Un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificity
- The antibody detects endogenous levels of TOB1 only when phosphorylated at serine 164.
- Purification
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- Immunogen
- TOB1 (phospho Ser164) antibody was raised against a peptide sequence around phosphorylation site of Serine 164 (A-V-S (p)-P-T) derived from Human TOB1.
- Isotype
- IgG
- Top Product
- Discover our top product TOB1 Primary Antibody
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- Application Notes
- Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store antibody at -20°C for up to one year.
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- Target
- Protein Tob1 (TOB1)
- Alternative Name
- TOB1 (TOB1 Products)
- Synonyms
- Tob antibody, Trob antibody, APRO5 antibody, APRO6 antibody, PIG49 antibody, TOB antibody, TROB antibody, TROB1 antibody, tob1 antibody, tob1l antibody, wu:fb54d02 antibody, wu:fb98h12 antibody, wu:fd15f10 antibody, zgc:65837 antibody, transducer of ErbB-2.1 antibody, transducer of ERBB2, 1 antibody, transducer of ERBB2, 1a antibody, transducer of ERBB2, 1 S homeolog antibody, transducer of ERBB2, 1b antibody, Tob1 antibody, TOB1 antibody, tob1a antibody, tob1.S antibody, tob1b antibody
- Background
- This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells.
- Molecular Weight
- 40 kDa
- Gene ID
- 10140
- NCBI Accession
- NP_001230806
- UniProt
- P50616
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