TUBA1/3/4 (pTyr272) antibody

Catalog No. ABIN2568521

Product Details

Target: TUBA1/3/4

Binding Specificity: pTyr272

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Specificity: The antibody detects endogenous levels of TUBA1/3/4 only when phosphorylated at tyrosine 272.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: TUBA1/3/4 (phospho Tyr272) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 272 (A-T-Y (p)-A-P) derived from Human TUBA1/3/4.

Isotype: IgG

Application Details

Application Notes: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store antibody at -20°C for up to one year.

Target Details

Target: TUBA1/3/4

Background: Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species.

Molecular Weight: 50-55 kDa

Gene ID: 7846, 10376, 84790

NCBI Accession: NP_001257328

UniProt: Q71U36, P68363, Q9BQE3, Q13748, Q6PEY2, P68366