ATRX antibody (AA 970-984)

Catalog No. ABIN2617356

Product Details anti-ATRX Antibody

Target: ATRX (helicase 2, X-linked (ATRX))

Binding Specificity: AA 970-984

Reactivity: Human, Monkey

Host: Goat

Clonality: Polyclonal

Conjugate: This ATRX antibody is un-conjugated

Application: ELISA

Specificity: Human RAD54 / ATRX. This antibody is expected to recognise all three reported isoforms (NP_000480.2, NP_612114.1, NP_612115.1).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-KKDQSDETSEDDKKQ from an internal region of human RAD54 / ATRX (NP_000480.2, NP_612114.1, NP_612115.1). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Monkey (100%), Gibbon (93%), Panda, Ferret, Rabbit, Pig (87%), Mouse (73%), Rat (67%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Peptide-ELISA (1:16000)

Usage: Peptide ELISA: antibody detection limit dilution 1:16000. Western blot: Not yet tested - our routinely used western blotting protocol does not allow detection of proteins as large as the expected size of 300  kDa according to the literature (PMID: 15591283). Therefore we cannot recommend an optimal concentration and the antibody is an aspiring product.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for ATRX

Target: ATRX (helicase 2, X-linked (ATRX))

Alternative Name: ATRX (ATRX Products)

Synonyms: ATR2 antibody, JMS antibody, MRXHF1 antibody, RAD54 antibody, RAD54L antibody, SFM1 antibody, SHS antibody, XH2 antibody, XNP antibody, ZNF-HX antibody, 4833408C14Rik antibody, AI447451 antibody, DXHXS6677E antibody, HP1-BP38 antibody, Hp1bp2 antibody, Hp1bp38 antibody, MRXS3 antibody, Rad54 antibody, Xnp antibody, atrx antibody, rad54 antibody, atrxl antibody, wu:fb26e12 antibody, wu:fb52h08 antibody, wu:fb72g09 antibody, wu:fb94e07 antibody, zgc:66223 antibody, ATRX, chromatin remodeler antibody, alpha thalassemia/mental retardation syndrome X-linked L homeolog antibody, alpha thalassemia/mental retardation syndrome X-linked homolog (human) antibody, ATRX antibody, Atrx antibody, atrx.L antibody, atrx antibody

Background: Name/Gene ID: ATRX

Synonyms: ATRX, ATP-dependent helicase ATRX, ATR2, Juberg-Marsidi syndrome, JMS, RAD54, RAD54 homolog, SFM1, MRXHF1, XH2, XNP, Transcriptional regulator ATRX, ZNF-HX, X-linked nuclear protein, SHS, Helicase 2, X-linked, X-linked helicase II, Zinc finger helicase

Gene ID: 546

NCBI Accession: NP_000480, NP_612114, NP_612115