CDK5 antibody (AA 273-292)

Catalog No. ABIN2618909

This Rabbit Polyclonal antibody specifically detects CDK5 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Monkey, Pig, Sheep, Horse, Rabbit and Bat.

Quick Overview for CDK5 antibody (AA 273-292) (ABIN2618909)

Target: CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

Reactivity: Human, Mouse, Rat, Cow, Monkey, Pig, Sheep, Horse, Rabbit, Bat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CDK5 Antibody

Binding Specificity: AA 273-292

Specificity: Isoform 1 is ubiquitously expressed. Accumulates in cortical neurons (at protein level). Isoform 2 has only been detected in testis, skeletal muscle, colon, bone marrow and ovary. .

Cross-Reactivity (Details): No cross reactivity with other proteins.

Purification: Immunogen affinity purified

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Cdk5(273-292aa QRISAEEALQHPYFSDFCPP), identical to the related rat and mouse sequences.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2 HPO4, 0.05 mg Thimerosal, 0.05 mg sodium azide per 100 μg antibody.

Preservative: Sodium azide, Thimerosal (Merthiolate)

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid freeze-thaw cycles.

Target Details for CDK5

Target: CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

Alternative Name: CDK5

Background: Name/Gene ID: CDK5
Subfamily: CDC2/CDK
Family: Protein Kinase

Synonyms: CDK5, CDKN5, Cell division protein kinase 5, Crk6, Cyclin-dependent kinase 5, Protein kinase CDK5 splicing, PSSALRE, TPKII catalytic subunit

Gene ID: 1020

Pathways: Cell Division Cycle, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis