GFAP antibody

Catalog No. ABIN2621286

Product Details anti-GFAP Antibody

Target: GFAP (Glial Fibrillary Acidic Protein (GFAP))

Reactivity: Human, Rat, Mouse, Pig, Chicken

Host: Mouse

Clonality: Monoclonal

Conjugate: This GFAP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: Recognizes GFAP in human, mouse, rat, porcine and chicken. The antibody reacts with the carboxyterminal cys II fragment of GFAP as determined by western blotting and does not cross react with vimentin.

Purification: Purified

Immunogen: G-A-5 is a mouse monoclonal IgG1 antibody derived by fusion of PA1 mouse myeloma cells with spleen cells from BALB/c mice immunized with purified GFAP from porcine spinal cord.

Type of Immunogen: Cells

Clone: G-A-5

Isotype: IgG1

Application Details

Application Notes: Approved: ICC, IHC, IHC-Fr, IHC-P, WB

Usage: Glial fibrillary acidic protein(GFAP) is a class III intermediate filament protein, a cytoskeletal protein that is located within the cytoplasm of astrocyctes and other glial cells e. g. Schwann cells and ependymal cells. In the central nervous system, GFAP is the major intermediate filament protein of mature astrocytes. GFAP plays an important role in maintaining the structure and stability of astrocytes during development and has also been shown to be involved in cellular communication, motility and mitosis. Mutations in GFAP give rise to Alexander disease, a rare and fatal disease of the central nervous system. Antibodies recognizing GFAP are commonly used to identify cells of astrocytic origin under normal and pathological conditions.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C, or in small aliquots at -20°C.

Target Details for GFAP

Target: GFAP (Glial Fibrillary Acidic Protein (GFAP))

Alternative Name: GFAP (GFAP Products)

Synonyms: GFAP antibody, AI836096 antibody, cb345 antibody, etID36982.3 antibody, gfapl antibody, wu:fb34h11 antibody, wu:fk42c12 antibody, xx:af506734 antibody, zgc:110485 antibody, glial fibrillary acidic protein antibody, GFAP antibody, LOC100136168 antibody, gfap antibody, Gfap antibody

Background: Name/Gene ID: GFAP

Synonyms: GFAP

Gene ID: 2670