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LAG3 antibody (AA 70-99)

LAG3 Reactivity: Human ICC, Func Host: Mouse Monoclonal 17B4 unconjugated

Catalog No. ABIN2624682

Datasheet as PDF

Target See all LAG3 Antibodies

LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
Binding Specificity
15

14

9

7

6

4

3

3

3

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 70-99
Reactivity
87

34

10

5

4

2

1

1

1
Human
Host
52

34

7

4
Mouse
Compatible Secondaries
Clonality
53

41

1
Monoclonal
Conjugate
51

6

6

3

3

3

3

3

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This LAG3 antibody is un-conjugated
Application
69

36

30

29

24

22

15

13

12

10

10

5

5

2

2

1

1

1

1

1
Immunocytochemistry (ICC), Functional Studies (Func)

Specificity

Recognizes the 30 aa extra-loop of the first N-terminal D1 domain of human LAG-3.

Purification

Protein A purified from tissue culture supernatant

Immunogen

Synthetic peptide corresponding to 30 aa (GPPAAAPGHPLAPGPHPAAPSSWGPRPRRY) from the first N-terminal D1 domain of human LAG-3 (lymphocyte activation gene-3). Percent identity by BLAST analysis: Human (100%), Gorilla (93%), Gibbon (90%), Monkey (83%).

Type of Immunogen: Synthetic peptide

Clone

17B4

Isotype

IgG1

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LAG3 Reactivity: Human WB, ELISA, IHC, IP, FACS, ICC Host: Mouse Monoclonal L4-PL33 unconjugated

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LAG3 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated

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LAG3 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 29-450) antibody
LAG3 Reactivity: Human WB, ELISA, IF Host: Rabbit Polyclonal unconjugated

anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 209-451) antibody
LAG3 Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 201-300) antibody
LAG3 Reactivity: Human, Mouse WB, ELISA, ICC, IHC (p), IF (p), IHC (fro), IF (cc) Host: Rabbit Polyclonal unconjugated

Application Notes

Approved: Func, ICC

Usage: Functional Application - Inhibition. Immunohistochemistry - Frozen sections (1:150. Immunoprecipitation - 10 μg/mL. Western Blot - 5 μg/mL.

Comment

Target Species of Antibody: Human

Restrictions

For Research Use only
Format

Liquid

Concentration

Lot specific

Buffer

PBS, 0.02 % sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice

Avoid freeze-thaw cycles.

Storage

4 °C,-20 °C

Storage Comment

Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Target

LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Alternative Name

LAG3 (LAG3 Products)

Synonyms

CD223 antibody, LAG-3 antibody, Ly66 antibody, lymphocyte activating 3 antibody, lymphocyte-activation gene 3 antibody, LAG3 antibody, Lag3 antibody

Background

Name/Gene ID: LAG3

Synonyms: LAG3, CD223 antigen, LAG-3, Protein FDC, CD223, FDC, Lymphocyte-activation gene 3

Gene ID

3902

Pathways

Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints