MAP3K1 antibody (AA 1418-1432)

Catalog No. ABIN2625096

The Rabbit Polyclonal anti-MAP3K1 antibody has been validated for WB, IHC and IHC (p). It is suitable to detect MAP3K1 in samples from Human, Mouse, Rat, Monkey, Rabbit, Pig, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio), Bat, Chicken, Sheep and Xenopus laevis.

Quick Overview for MAP3K1 antibody (AA 1418-1432) (ABIN2625096)

Target: MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1))

Reactivity: Human, Mouse, Rat, Monkey, Rabbit, Pig, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio), Bat, Chicken, Sheep, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP3K1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MAP3K1 Antibody

Binding Specificity: AA 1418-1432

Cross-Reactivity (Details): No cross reactivity with other proteins.

Purification: Immunogen affinity purified

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human MEKK1(1418-1432aa PEVLRGQQYGRSCDV), identical to the related rat and mouse sequences.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2 HPO4, 0.05 mg Thimerosal, 0.05 mg sodium azide per 100 μg antibody.

Preservative: Sodium azide, Thimerosal (Merthiolate)

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid freeze-thaw cycles.

Target Details for MAP3K1

Target: MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1))

Alternative Name: MAP3K1 / MEKK1

Background: Name/Gene ID: MAP3K1
Subfamily: MAP3K
Family: Protein Kinase

Synonyms: MAP3K1, MAPK/ERK kinase kinase 1, MAPKKK1, MAP/ERK kinase kinase 1, MEK kinase 1, MEKK, MEKK 1, MEKK1, SRXY6

Gene ID: 4214

Pathways: MAPK Signaling, Interferon-gamma Pathway, Caspase Cascade in Apoptosis, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Actin Filament Polymerization, Toll-Like Receptors Cascades