Myeloperoxidase antibody

Catalog No. ABIN2625712

Product Details anti-Myeloperoxidase Antibody

Target: Myeloperoxidase (MPO)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Myeloperoxidase antibody is un-conjugated

Application: Flow Cytometry (FACS)

Purification: Chromatography

Clone: 8E6

Isotype: IgG1

Application Details

Application Notes: Approved: Flo

Usage: Myeloperoxidase (MPO) is a glycoprotein present in the azurophil (primary) granules of myeloid cells, which appears in the myeloblast stage of myeloid cell differentiation. MPO is he most common functional protein of myeloid cells and is involved in the inflammatory response. It helps to kill microbes by breaking down peroxide in the presence of halide ions, contributing to the bactericidal function of granulocytes. The primary translation product of MPO undergoes glycosylation with production of the 89 kD heme-free apopro-MPO form followed by incorporation of heme and conversion into the enzymatically active pro-MPO form. Subsequently, pro-MPO becomes targeted to azurophil granules where final processing occurs to produce mature dimeric MPO consisting of the 59-64 kD MPO alpha -chain and the 14 kD MPO beta -chain.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 1 % BSA, 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze. Protect from light.

Target Details for Myeloperoxidase

Target: Myeloperoxidase (MPO)

Alternative Name: MPO / Myeloperoxidase (MPO Products)

Synonyms: mKIAA4033 antibody, MPO antibody, LOC100335032 antibody, POX2' antibody, XPOX2' antibody, mpo antibody, mpo-A antibody, pmr-1 antibody, pmr1 antibody, pox2 antibody, xpox2 antibody, myeloperoxidase antibody, myeloperoxidase L homeolog antibody, MPO antibody, Mpo antibody, LOC100335032 antibody, mpo.L antibody

Background: Name/Gene ID: MPO

Synonyms: MPO, Myeloperoxidase precursor, Myeloperoxidase

Gene ID: 4353

Pathways: Chromatin Binding