RIPK1 antibody (AA 133-422)

Catalog No. ABIN2627659

The Mouse Monoclonal anti-RIPK1 antibody (Clone 2G3) (ABIN2627659) specifically detects RIPK1 in WB, IHC and IHC (p). The antibody is reactive with Human and Dog samples.

Quick Overview for RIPK1 antibody (AA 133-422) (ABIN2627659)

Target: RIPK1 (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1))

Reactivity: Human, Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This RIPK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 2G3

Product Details anti-RIPK1 Antibody

Binding Specificity: AA 133-422

Specificity: Human RIP

Purification: Protein A/G purified

Immunogen: Human recombinant protein fragment corresponding to amino acids 133-422 of human RIPK1(NP_003795) produced in E. coli.

Type of Immunogen: Recombinant protein

Isotype: IgG2a

Application Details

Application Notes: Approved: IHC, IHC-P (10 μg/mL), WB (1:500)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.3, 1 % BSA, 50 % glycerol, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for RIPK1

Target: RIPK1 (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1))

Alternative Name: RIPK1 / RIP

Background: Name/Gene ID: RIPK1
Subfamily: RIP
Family: Protein Kinase

Synonyms: RIPK1, Cell death protein RIP, Receptor interacting protein, RIP1, RIP, RIP-1, Protein kinase rip, Receptor-interacting protein 1, Rinp

Gene ID: 8737

NCBI Accession: NP_003795

Pathways: NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Activation of Innate immune Response, Inositol Metabolic Process, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome, Ubiquitin Proteasome Pathway