PLAUR antibody
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- Target See all PLAUR Antibodies
- PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
- Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PLAUR antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human PLAUR
- Isotype
- IgG
- Top Product
- Discover our top product PLAUR Primary Antibody
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- Application Notes
- WB 1:500 - 1:2000
- Comment
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Expressed in neurons of the rolandic area of the brain (at protein level), Expressed in the brain
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20C. Avoid freeze / thaw cycles.
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- Target
- PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
- Alternative Name
- PLAUR (PLAUR Products)
- Synonyms
- Cd87 antibody, u-PAR antibody, uPAR antibody, CD87 antibody, U-PAR antibody, UPAR antibody, URKR antibody, Par antibody, Plaur3 antibody, uPAR-2 antibody, uPAR-3 antibody, PLAUR antibody, plasminogen activator, urokinase receptor antibody, Plaur antibody, PLAUR antibody
- Background
- This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.
- Molecular Weight
- 36.978 kDa
- Gene ID
- 5329
- UniProt
- Q03405
- Pathways
- Inositol Metabolic Process
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