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MMP 9 antibody
MMP9
Reactivity: Human
WB, IHC (p), IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MMP 9 Antibody
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Target
See all MMP 9 (MMP9) Antibodies
MMP 9 (MMP9)
(Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9))
Reactivity
All reactivities for MMP 9 antibodies
Human
Host
All hosts for MMP 9 antibodies
Rabbit
Clonality
All clonalities for MMP 9 antibodies
Polyclonal
Conjugate
All conjugates for MMP 9 antibodies
This MMP 9 antibody is un-conjugated
Application
All applications for MMP 9 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
Specificity
This antibody detects endogenous levels of MMP-9 protein. (region surrounding Trp680)
Cross-Reactivity (Details)
Species reactivity (tested):Human.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Purity
> 95 % pure by SDS-PAGE
Top Product
Discover our top product MMP9 Primary Antibody
Alternatives
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anti-Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9) (AA 611-707) antibody
MMP9
Reactivity: Human, Rat, Mouse, Rabbit
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
anti-Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9) (AA 151-250) antibody
MMP9
Reactivity: Human, Rat, Mouse, Rabbit, Dog
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
anti-Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9) (N-Term) antibody
MMP9
Reactivity: Human, Rat, Mouse, Rabbit, Cow, Dog, Horse, Zebrafish (Danio rerio), Guinea Pig, Sheep
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
1,0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
DO NOT FREEZE!
Storage
4 °C
Storage Comment
Store the antibody undiluted at 2-8 °C.
Target Details for MMP 9
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Target
MMP 9 (MMP9)
(Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9))
Alternative Name
MMP-9 (MMP9 Products )
Synonyms
CLG4B antibody, GELB antibody, MANDP2 antibody, MMP-9 antibody, AW743869 antibody, B/MMP9 antibody, Clg4b antibody, pro-MMP-9 antibody, mmp-9 antibody, fgMMP-9 antibody, mmp9 antibody, ZFMMP-9 antibody, wu:fb02g06 antibody, wu:fb07b05 antibody, wu:fi98c09 antibody, wu:fj05a08 antibody, zgc:64165 antibody, clg4b antibody, gelb antibody, mandp2 antibody, matrix metallopeptidase 9 antibody, collagenase antibody, matrix metalloproteinase 9 antibody, matrix metallopeptidase 9 S homeolog antibody, MMP9 antibody, RB3913 antibody, BPSS0666 antibody, Sbal_3732 antibody, Bcer98_0486 antibody, Shew185_0630 antibody, Shal_3056 antibody, Sbal195_0657 antibody, Lbys_3550 antibody, Palpr_2084 antibody, Mmp9 antibody, mmp9 antibody, mmp9.S antibody
Background
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or taphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-9 (also designated 92- kDa type IV collagenase or gelatinase B) has been shown to degrade bone collagens in concert with MMP-1 (also designated interstitial collagenase, fibroblast collagenase or collagenase-1), and cysteine proteases and may play a role in bone osteoclastic resorption. MMP-1 is down-regulated by p53, and abnormality of p53 expression may contribute to joint degradation in rheumatoid arthritis by regulating MMP-1 expression.Synonyms: 92 kDa gelatinase, 92 kDa type IV collagenase, CLG4B, GELB, Gelatinase B, MMP9, Matrix metalloproteinase-9
Molecular Weight
approx. 78 kDa
Gene ID
4318
NCBI Accession
NP_004985
UniProt
P14780
Pathways
Cellular Response to Molecule of Bacterial Origin , Positive Regulation of Immune Effector Process , CXCR4-mediated Signaling Events
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