CEACAM1/5/6 antibody (Alexa Fluor 488)

Catalog No. ABIN2657468

Product Details anti-CEACAM1/5/6 Antibody (Alexa Fluor 488)

Target: CEACAM1/5/6 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/5/6 (CEACAM1/5/6))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CEACAM1/5/6 antibody is conjugated to Alexa Fluor 488

Application: Flow Cytometry (FACS)

Purification: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.

Clone: ASL-32

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C

Target Details for CEACAM1/5/6

Target: CEACAM1/5/6 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/5/6 (CEACAM1/5/6))

Alternative Name: CD66a/c/e

Background: The ASL-32 mAb reacts with an antigen epitope shared by CD66a, c and e. CD66a/c/e are members of the CEA (carcinoembryonic antigen) family of the Ig superfamily. CD66 plays a role in hemophilic and heterophilic adhesion. CD66a, also known as CEACAM1 and BGP (biliary glycoprotein), is mainly expressed on granulocytes, binds to CD66a, c, e, and CD62E. CD66c (known as CEACAM6, NCA) is expressed on granulocytes and epithelial cells. The ligands of CD66c are CD66a-e, CD62E and Galectins. CD66e molecule is also called CEA or CEACAM5, and is primarily found on epithelial cells. CD66e binds to CD66a, c and e.