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LILRA4 antibody (Alexa Fluor 647)
LILRA4
Reactivity: Human
FACS
Host: Mouse
Monoclonal
17G10-2
Alexa Fluor 647
Product Details anti-LILRA4 Antibody (Alexa Fluor 647)
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Target
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LILRA4
(Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 4 (LILRA4))
Reactivity
All reactivities for LILRA4 antibodies
Human
Host
All hosts for LILRA4 antibodies
Mouse
Clonality
All clonalities for LILRA4 antibodies
Monoclonal
Conjugate
All conjugates for LILRA4 antibodies
This LILRA4 antibody is conjugated to Alexa Fluor 647
Application
All applications for LILRA4 antibodies
Flow Cytometry (FACS)
Purification
The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.
Clone
17G10-2
Isotype
IgG1 kappa
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Protect from prolonged exposure to light. Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C
Target Details for LILRA4
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Target
LILRA4
(Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 4 (LILRA4))
Alternative Name
CD85g (LILRA4 Products )
Synonyms
ILT7 antibody, CD85g antibody, leukocyte immunoglobulin like receptor A4 antibody, LILRA4 antibody
Background
ILT7 (immunoglobulin-like transcript 7) is a member of leukocyte immunoglobulin-like receptor (LIR or LILR) gene family, also known as CD85g and LILRA4. It contains four extracellular Ig domains. In association with FcεR1γ, ILT7 forms a receptor complex that transduces ITAM-mediated signals. ILT7 is specifically expressed on plasmacytoid dendritic cells (pDCs), but not on myeloid dendritic cells and other peripheral blood leukocytes. ILT7 negatively regulates the innate immune functions of human pDCs. Cross-linking 17G10.2 antibody is able to trigger ILT7 mediated signaling.
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