The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
MGC179455 antibody, CLL-1 antibody, CLL1 antibody, DCAL-2 antibody, MICL antibody, D230024O04 antibody, KLRL1 antibody, Micl antibody, C-type lectin domain family 12 member A antibody, C-type lectin domain family 12, member a antibody, C-type lectin domain family 12, member A antibody, CLEC12A antibody, Clec12a antibody
Background
CD371 (CLEC12A), also known as DCAL-2, MICL or CLL-1, is a 30 kD type II transmembrane protein with extracellular C-type lectin domains, belonging to the C-type lectin family. It is expressed on monocytes, granulocytes, NK cells, and basophils. Its cytoplasmic ITIM motif modulates signaling cascades and is involved in phosphorylation of tyrosine residues in MAP kinases.