VISTA
(V-type immunoglobulin domain-containing suppressor of T-cell activation (VISTA))
Reactivity
Mouse
Host
Armenian Hamster
Clonality
Monoclonal
Conjugate
This VISTA antibody is conjugated to APC
Application
ELISA (Detection)
Purification
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
PD-1H, also known as VISTA, is a 309 aa type I transmembrane protein, composed of seven exons. PD-1H has one Ig-V like domain, and its sequence is similar to the Ig-V domains of the members of CD28 and B7 families. PD-1H is expressed by a subset of T cells, macrophages, dendritic cells, neutrophils, and NK cells. It has been proposed that PD-1H can be useful to modulate the host immune response to allogeneic transplants.