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VISTA antibody
VISTA
Reactivity: Mouse
WB, IHC, IF, IP
Host: Armenian Hamster
Monoclonal
MH5A
unconjugated
Product Details anti-VISTA Antibody
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Target
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VISTA
(V-type immunoglobulin domain-containing suppressor of T-cell activation (VISTA))
Reactivity
All reactivities for VISTA antibodies
Mouse
Host
All hosts for VISTA antibodies
Armenian Hamster
Clonality
All clonalities for VISTA antibodies
Monoclonal
Conjugate
All conjugates for VISTA antibodies
This VISTA antibody is un-conjugated
Application
All applications for VISTA antibodies
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
Purification
The antibody was purified by affinity chromatography.
Clone
MH5A
Isotype
IgG
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Discover our top product VISTA Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for VISTA
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Target
VISTA
(V-type immunoglobulin domain-containing suppressor of T-cell activation (VISTA))
Alternative Name
PD-1H (VISTA Products )
Synonyms
MGC112715 antibody, MGC151567 antibody, B7-H5 antibody, B7H5 antibody, GI24 antibody, PP2135 antibody, SISP1 antibody, Dies1 antibody, VISTA antibody, V-set immunoregulatory receptor antibody, vsir antibody, Vsir antibody, VSIR antibody
Background
PD-1H, also known as VISTA, is a 309 aa type I transmembrane protein, composed of seven exons. PD-1H has one Ig-V like domain, and its sequence is similar to the Ig-V domains of the members of CD28 and B7 families. PD-1H is expressed by a subset of T cells, macrophages, dendritic cells, neutrophils, and NK cells. It has been proposed that PD-1H can be useful to modulate the host immune response to allogeneic transplants.
Pathways
Cancer Immune Checkpoints
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