CCL11 antibody

Catalog No. ABIN7517588

Product Details anti-CCL11 Antibody

Target: CCL11 (Chemokine (C-C Motif) Ligand 11 (CCL11))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This CCL11 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Purification: Affinity purified.

Clone: L402H11

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Upon receipt, store undiluted between 2°C and 8°C.

Target Details for CCL11

Target: CCL11 (Chemokine (C-C Motif) Ligand 11 (CCL11))

Alternative Name: CCL11 (CCL11 Products)

Synonyms: SCYA11 antibody, Scya11 antibody, eotaxin antibody, Eotaxin antibody, C-C motif chemokine ligand 11 antibody, chemokine (C-C motif) ligand 11 antibody, CCL11 antibody, Ccl11 antibody

Background: CCL11 selectively recruits eosinophils through binding to the chemokine receptor CCR3 during allergic response. CCL11 production is upregulated in response to several proimflammatory cytokines, such as IL-4, IL-13, TNF-α, and IFN-α, produced by mast cells and Th2 lymphocytes. CCL11 has been reported to stimulate eosinophil release from bone marrow, resulting in an elevated level of circulating eosinophils.

Pathways: Regulation of Actin Filament Polymerization, The Global Phosphorylation Landscape of SARS-CoV-2 Infection