Histone H4 antibody (2meArg3 (asymetric))

Catalog No. ABIN2668871

Product Details anti-Histone H4 Antibody

Target: Histone H4

Binding Specificity: 2meArg3 (asymetric)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Histone H4 antibody is un-conjugated

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP), Dot Blot (DB)

Purification: Protein A Chromatography

Immunogen: This Histone H4 dimethylArg3, asymmetric antibody was raised against a synthetic peptide containing dimethylArg3 (asymmetric) of human histone H4.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage: -20 °C

Storage Comment: Antibodies in solution can be stored at -20 °C for 2 years.

Expiry Date: 6 months

References for anti-Histone H4 antibody (ABIN2668871)

Gao, Zhao, Zhang, Lu, Liu, Geng, Huang, Zhang, Lu: "The dual function of PRMT1 in modulating epithelial-mesenchymal transition and cellular senescence in breast cancer cells through regulation of ZEB1." in: Scientific reports, Vol. 6, pp. 19874, (2016) (PubMed).

Tibshirani, Tradewell, Mattina, Minotti, Yang, Zhou, Strong, Hayward, Durham: "Cytoplasmic sequestration of FUS/TLS associated with ALS alters histone marks through loss of nuclear protein arginine methyltransferase 1." in: Human molecular genetics, Vol. 24, Issue 3, pp. 773-86, (2015) (PubMed).

Poulard, Rambaud, Hussein, Corbo, Le Romancer: "JMJD6 regulates ERα methylation on arginine." in: PLoS ONE, Vol. 9, Issue 2, pp. e87982, (2014) (PubMed).

Kolodziej, Kuvardina, Oellerich, Herglotz, Backert, Kohrs, Buscató, Wittmann, Salinas-Riester, Bonig, Karas, Serve, Proschak, Lausen: "PADI4 acts as a coactivator of Tal1 by counteracting repressive histone arginine methylation." in: Nature communications, Vol. 5, pp. 3995, (2014) (PubMed).

Wang, Zhu, Chen, Li, Peng, Chen, Zou, Zhang, Jin, Yang, Wu, Niu, Gong, Teng, Shi: "Crystal structure of arginine methyltransferase 6 from Trypanosoma brucei." in: PLoS ONE, Vol. 9, Issue 2, pp. e87267, (2014) (PubMed).

Shia, Okumura, Yan, Sarkeshik, Lo, Matsuura, Komeno, Zhao, Nimer, Yates, Zhang: "PRMT1 interacts with AML1-ETO to promote its transcriptional activation and progenitor cell proliferative potential." in: Blood, Vol. 119, Issue 21, pp. 4953-62, (2012) (PubMed).

Dhar, Lee, Kan, Voigt, Ma, Shi, Reinberg, Lee: "Trans-tail regulation of MLL4-catalyzed H3K4 methylation by H4R3 symmetric dimethylation is mediated by a tandem PHD of MLL4." in: Genes & development, Vol. 26, Issue 24, pp. 2749-62, (2012) (PubMed).

Sun, Wang, Lv, Yang, Liu, Bao, Gong, Xu: "Structural insights into protein arginine symmetric dimethylation by PRMT5." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 51, pp. 20538-43, (2011) (PubMed).

Target Details for Histone H4

Target: Histone H4

Abstract: Histone H4 Products

Synonyms: hist1h4l antibody, H1ft antibody, Hist4 antibody, Hist4h4 antibody, H4 antibody, X04652 antibody, FO108 antibody, H4/n antibody, H4F2 antibody, H4FN antibody, HIST2H4 antibody, H4C13 antibody, H4C7 antibody, F8N16.2 antibody, F8N16_2 antibody, histone H4 antibody, BcDNA:RH52884 antibody, CG3379 antibody, Dmel\CG3379 antibody, H4r antibody, His4-88CD antibody, His4R antibody, histone cluster 1, H4a L homeolog antibody, histone cluster 1 H4 family member B antibody, histone cluster 2, H4 antibody, histone cluster 2 H4 family member a antibody, histone H4 antibody, Histone H4 replacement antibody, Histone H4 antibody, hist1h4a.L antibody, Hist1h4b antibody, Hist2h4 antibody, HIST2H4A antibody, H4 antibody, H4C14 antibody, HIS4 antibody, HIST2H4 antibody, His4r antibody, his-38 antibody

Molecular Weight: 8 kDa

Gene ID: 121504